Mild H5N1 cases weren’t missed in Cambodian outbreak

first_imgMar 27, 2006 (CIDRAP News) – Researchers who looked for mild or asymptomatic human cases of H5N1 avian influenza following an outbreak in Cambodia last year didn’t find any, challenging the view that human cases have gone undetected, according to findings presented last week.The research described Mar 20 at the International Conference on Emerging Infectious Diseases in Atlanta implies that surveillance for human cases might be more effective than some experts assumed, according to a story by the Canadian Press (CP). However, the findings also imply that the case-fatality rate for avian flu is higher than some experts thought.Dr. Philippe Buchy and his colleagues at the Institut Pasteur in Phnom Penh last spring tested blood samples from 351 residents of a Cambodian village where poultry and one person had died of avian flu, the CP reported. No signs of antibodies to H5N1 were found in the samples, indicating the residents had not suffered even mild cases of avian flu.Some of the people tested had “significant” exposure to poultry or infected people, the story said. For example, a doctor who inserted a tube down an H5N1 patient’s windpipe without wearing any protective gear did not show any antibodies indicating infection. The same was true for other healthcare workers, including two veterinarians who had autopsied H5N1-infected birds. The healthcare workers did not know at the time they were dealing with avian flu cases.”We didn’t find any cases of H5N1, so nobody seems to have been asymptomatic or with mild symptoms during this outbreak in Cambodia,” Buchy told the CP.On the bright side, Buchy was quoted as saying the data indicate the virus still finds it difficult to jump from poultry to humans.Dr. Nancy Cox, head of the influenza branch at the US Centers for Disease Control and Prevention (CDC) in Atlanta, concurred with Buchy, but added: “On the other side of the coin, it means that the case-fatality rate is still very high. And that is a negative thing.”Experts have suggested that the current case fatality rate for avian flu, about 56%, could be inaccurate because milder or asymptomatic cases have not been identified.”The work in Cambodia is extremely important because it shows that we really aren’t missing that much,” Cox told the CP. However, she added that it is important to conduct research on a larger scale to determine whether mild or asymptomatic cases are occurring, and said such studies are planned.last_img read more

EPL analysis: 7 things we learned from Saturday’s games

first_imgChelsea’s top-four challenge is already over, while four-goal Tottenham still concern in attack. Oh, and we propose a new system to end the injury-time debate for good.…1) Chelsea can forget top fourSince Guus Hiddink uttered the unwise words that fourth position was possible, Chelsea have collected two points from as many games – effectively ending the shortest ever European challenge. Their next three Premier League games are Arsenal (a), Watford (a) and Manchester United (h). It’s got to the stage where they could feasibly lose all three and, if they do, expect the words ‘relegation battle’ to be lumped into the first sentence of all future match reports. If John Terry’s controversial leveller hadn’t crept in during Chelsea’s tussle with Everton, it may have already commenced. Which brings us onto…2) It’s time to overhaul injury time To blow or not to blow, that is the question? It’s a dilemma that afflicts referees across the globe. Mike Jones found himself at the centre of that exact storm at Stamford Bridge, deciding to play over the allotted seven minutes of injury time – allowing Terry to score his offside winner. And he was probably right, given Ramiro Funes Mori’s one-man celebration dragged on for many, many seconds. But Roberto Martinez still fumed. The solution? Take time-keeping duties away from the referee. Instead, hand them to a fifth official, who surveys the match from the stands and can tot up exactly how much time should be added on, rather than simply rounding to the nearest minute. Then, when that time has passed, the match concludes when the ball next goes out of play. Simple. 3) Title could come down to Sergio Aguero v Olivier Giroud Leicester may be dreaming of the impossible, but the reality is the Premier League title race will probably boil down to Manchester City v Arsenal. Or, perhaps more accurately, Sergio Aguero v Olivier Giroud. One is plagued by fitness woes, the other burdened with widespread condemnation. Sure, City are favourites with Aguero, but any injury would promote Giroud to the deadliest striker in the title race. Sporadic brilliance or consistent normality… which would you prefer?4) Tottenham still struggling to break teams down But Tottenham beat Sunderland 4-1, right? True, but look a little deeper and Spurs’ problem of old remains: their inability to break down teams. But for the introduction of debutant Jan Kirchhoff – inadvertently instrumental in the third and fourth goals – it may not have been so easy for Spurs. There is so much to admire about their high-pressing game, but it’s still unclear whether they can repeatedly unlock the tightest of defences. The 1-0 home defeat to Leicester in midweek proved as much.5) Leicester may already have the depth to go the distance Thought Leicester didn’t possess a squad capable of challenging for a top-four spot, or maybe even the title? The rise of Shinji Okazaki disputes that. Magnificent in the two games against Tottenham over the past week, the Japanese forward was an energetic presence as Leicester drew 1-1 with Aston Villa. He may not snatch the headlines as frequently as Jamie Vardy and Riyad Mahrez, but his contributions are imperative if Leicester are to complete the impossible. It’s these lesser-heralded stars, Danny Drinkwater and Christian Fuchs, that are keeping their charge ticking over. Perhaps Claudio Ranieri was right. Maybe they don’t need reinforcements in January. 6) Jonjo Shelvey has his mojo back Just as his hopes of making the plane for Euro 2016 were diminishing, Jonjo Shelvey burst back with a fine performance in Newcastle’s 2-1 win over West Ham. He was instrumental in both his side’s goals and barely missed a pass. Not bad for a player who was struggling to get in the Swansea team. It’s now feasible he could help send his old club down. His next task: get back into Roy Hodgson’s plans…7) Arsene Wenger may rue letting Benik Afobe leaveFebruary 7: Bournemouth v Arsenal. A first reunion for Benik Afobe and Arsenal since Arsene Wenger deemed him surplus to requirements. It may have been a mistake. Afobe, after scoring a hatful for Wolves, marked his Cherries debut with a goal and seems set for a permanent starting role at the Vitality Stadium. Never given a chance by Wenger, he could yet have a say in whether the title finally arrives at the Emirates. –last_img read more

Juventus gamble on Sarri delivering another style of Serie A title

first_imgFor Juventus sporting director Fabio Paratici all the pieces are in place for Sarri to deliver another style of football.“We’re very happy with what has been done. We bought de Ligt, who all the top teams wanted,” said Paratici.“We managed to buy him, along with two big players on free transfers: Rabiot and Ramsey, who were courted by many.“Juve has very high-level players in all departments, a squad of absolute value.”– ‘Removing scepticism’ –Juventus will be hoping these players and their new coach can implement the ‘Sarriball’ football philosophy: a fast-paced attacking style, that impressed during his time with Napoli.Brazilian left-back Alex Sandro insisted Sarri was already having an impact.“We can’t wait to start the season. We’ve already assimilated Sarri’s mentality and, we know what to do.“We all still have to improve naturally, but we are on the right path.”De Ligt also praised Sarri.“He  was one of the reasons that I wanted to join here, I’ve heard a lot of good things about him and I like his footballing philosophy and how he prepares his defence.”Sarri described coaching Juventus as “the crowning” moment of his 30-year managerial career.“I arrive surrounded by sceptics, but then I always am. I had the same at Empoli, Napoli and Chelsea.“In football, I know only one way of removing scepticism from the minds of people: by winning convincingly.“I haven’t won a lot, but I believe that having fun on the pitch doesn’t stop you winning.”Share on: WhatsApp Juventus want head coach Maurizio Sarri to point them in a fresh directionMilan, Italy | AFP | Juventus begin their Serie A campaign this weekend under new coach Maurizio cas the multiple Italian champions gamble on the veteran delivering another style of Serie A title.The Turin giants start their quest for a ninth consecutive title in Parma on Saturday but could be without Sarri on the bench after the 60-year-old was diagnosed with pneumonia on Monday.Sarri returns to Italy after one turbulent season in the Premier League with Chelsea, having previously coached his hometown team Napoli for three seasons.Chain-smoking Sarri’s appointment, in place of the clean cut Massimiliano Allegri who had delivered the last five of their Serie A titles, is a break in tradition for Juventus.But after also ditching their iconic black and white striped jersey last season, the club are looking for a change in direction.Despite their success Juventus have often been criticised for their boring defensive style of play.Club bosses want a more attractive eye-catching style of football in an attempt to increase their fan base outside of Italy.While Sarri’s only major title was the Europa League last season with Chelsea, he promises to give serial Italian champions Juventus a more dynamic style of play.Goalkeeper Gianluigi Buffon, returning to Turin after a season at Paris Saint-Germain, thinks the change of direction can pay off.“Those who follow the same path will always achieve the same results, so Juve are seeking the Champions League and wanted to try breaking away towards pastures new,” said the 41-year-old.“Sarri is not a revolution, nor a gamble. He simply represents an untested path, a whole other story.”Among Juventus’s rivals this season will be Carlo Ancelotti’s Napoli and Inter Milan, now coached by former Juventus boss Antonio Conte.But Juventus have spent big giving Sarri a stellar squad to target a 36th Scudetto and their first Champions League title since 1996.Cristiano Ronaldo, a player who Sarri insists “will make the difference”, will again be central to attack with newly-signed Dutch star Matthijs De Ligt the jewel in defense alongside veterans Giorgio Chiellini and Leonardo Bonucci.De Ligt’s Ajax sent Juventus crashing out of the Champions League last season.The midfield has been strengthened with PSG’s Adrien Rabiot and former Arsenal star Aaron Ramsey, both acquired on free transfers but on large salaries.last_img read more