Mild H5N1 cases weren’t missed in Cambodian outbreak

first_imgMar 27, 2006 (CIDRAP News) – Researchers who looked for mild or asymptomatic human cases of H5N1 avian influenza following an outbreak in Cambodia last year didn’t find any, challenging the view that human cases have gone undetected, according to findings presented last week.The research described Mar 20 at the International Conference on Emerging Infectious Diseases in Atlanta implies that surveillance for human cases might be more effective than some experts assumed, according to a story by the Canadian Press (CP). However, the findings also imply that the case-fatality rate for avian flu is higher than some experts thought.Dr. Philippe Buchy and his colleagues at the Institut Pasteur in Phnom Penh last spring tested blood samples from 351 residents of a Cambodian village where poultry and one person had died of avian flu, the CP reported. No signs of antibodies to H5N1 were found in the samples, indicating the residents had not suffered even mild cases of avian flu.Some of the people tested had “significant” exposure to poultry or infected people, the story said. For example, a doctor who inserted a tube down an H5N1 patient’s windpipe without wearing any protective gear did not show any antibodies indicating infection. The same was true for other healthcare workers, including two veterinarians who had autopsied H5N1-infected birds. The healthcare workers did not know at the time they were dealing with avian flu cases.”We didn’t find any cases of H5N1, so nobody seems to have been asymptomatic or with mild symptoms during this outbreak in Cambodia,” Buchy told the CP.On the bright side, Buchy was quoted as saying the data indicate the virus still finds it difficult to jump from poultry to humans.Dr. Nancy Cox, head of the influenza branch at the US Centers for Disease Control and Prevention (CDC) in Atlanta, concurred with Buchy, but added: “On the other side of the coin, it means that the case-fatality rate is still very high. And that is a negative thing.”Experts have suggested that the current case fatality rate for avian flu, about 56%, could be inaccurate because milder or asymptomatic cases have not been identified.”The work in Cambodia is extremely important because it shows that we really aren’t missing that much,” Cox told the CP. However, she added that it is important to conduct research on a larger scale to determine whether mild or asymptomatic cases are occurring, and said such studies are planned.last_img read more

Dodgers’ Clayton Kershaw encouraged by MRI, but his immediate future holds few certainties

first_img Dodgers’ Dave Roberts says baseball’s unwritten rules ‘have changed, should change’ Kershaw at least seemed encouraged that his injury was isolated. He said that his back, a source of great worry in years past, has felt fine all season. Having no history of biceps injuries, Kershaw had little basis for a prediction, but he offered hope that he would begin playing catch “pretty soon.” Manager Dave Roberts ventured so far as to predict that might happen by the end of this week.If faith is the substance of things hoped for, it is the rare source of substance in Kershaw’s prognosis.“Ultimately, I try to do the best I can to prevent injuries, to stay healthy, but sometimes it’s unavoidable,” Kershaw said. “I have some ideas going forward with (pitching coach Rick Honeycutt), and different things to try and figure some things out.”This is not a new idea. Roberts revealed that Kershaw and Honeycutt have been working on Kershaw’s mechanics “over the last few weeks.” Whatever their reason, whatever their goal, that work did yield the desired results.Kershaw’s four-seam fastball has averaged 91-92 mph this season, the lowest of any period in his major-league career. He’s phased the pitch in and out over the course of seven starts. By start No. 7, last week in Phoenix, the four-seamer accounted for 39 of Kershaw’s 101 pitches. Sign up for our Inside the Dodgers newsletter. Be the best Dodger fan you can be by getting daily intel on your favorite team. Subscribe here.Feeding opponents a steady diet of curveballs and sliders, Kershaw was more effective than not. His earned-run average is a solid 2.86, and he’s struck out 26.5 percent of opponents. Could an increase in breaking balls lead to more wear and tear on the biceps?“I don’t think so,” Kershaw said.Count a biceps injury among the many new obstacles Kershaw has faced in 2018. The pile is big. It includes a declining fastball, a mechanical mystery, and a team that is presently desperate for a No. 1 starter in what appears to be a World Series hangover. All at the not-quite-tender age of 30.“I’ve joked about being old, but I don’t think it has anything to do with deterioration,” Kershaw said. “There’s some things I can do to get better. … I’m not worried about deteriorating.”TURNER TURNS A CORNERThird baseman Justin Turner will get his first look at live pitching each of the next two days, he said.The club will stage simulated games at Dodger Stadium that will allow Turner to get at-bats against minor league pitchers, run the bases, and take grounders at third.“It’s like a super fast-forward rehab game,” he said. “You get everything done at once. Sometimes you go on a rehab game, you get one ground ball hit to you, you get out three times and don’t get to run the bases. This way you get to do everything.”By the end of the week, Turner could be out on a minor league rehab assignment. Roberts said Turner is in line to rejoin the Dodgers during next week’s trip to Miami and Washington, D.C.ALSOOutfielder Yasiel Puig went 0 for 4 in his first rehab game with Class-A Rancho Cucamonga. He played eight innings in right field. Puig is on the 10-day disabled list with injuries to his hip and ankle. … Infielder Logan Forsythe (shoulder) is also in line to join the Dodgers on next week’s trip, Roberts said. … The Cincinnati Reds made a change to their weekend rotation plans, trading catcher Devin Mesoraco to the New York Mets for right-handed pitcher Matt Harvey. According to the team, Harvey will join the Reds in Los Angeles for the four-game series beginning Thursday.UP NEXTDodgers (LHP Alex Wood, 0-3, 3.83 ERA) vs. Diamondbacks (LHP Patrick Corbin, 4-0, 2.15), Wednesday, 7 p.m., SportsNet LA (where available)Related Articles Dodgers bench slumping Cody Bellinger for a day Whicker: Dustin May yet another example of the Dodgers’ eye for pitching Dodgers’ hot-hitting Corey Seager leaves game with back injury LOS ANGELES — The translucent wax paper covering Clayton Kershaw Injury Watch was replaced with a sheer burqa on Tuesday, when the Dodgers pitcher offered the first details about the tendinitis in his left biceps.The symptoms, which Kershaw described as “pretty generic,” first cropped up toward the end of his most recent start May 1 in Phoenix. When he tried playing catch over the weekend in Monterrey, Mexico, the three-time Cy Young Award winner said he was still in pain.“I was able to throw a little bit,” he said. “(Throwing off the mound in the) bullpen was going to be pretty difficult. That’s why I pulled the plug.”Kershaw was placed on the 10-day disabled list Sunday. He returned to Los Angeles, where an MRI revealed no structural damage. The Dodgers did not offer a timetable for Kershaw’s return at first, and even the MRI results couldn’t coax any more of a prediction from anyone at the ballpark Tuesday. Dodgers’ Justin Turner looking rejuvenated on defense Newsroom GuidelinesNews TipsContact UsReport an Errorlast_img read more