Status woe: Cavaliers not planning changes amid slump

first_imgAFPINDEPENDENCE, Ohio — As LeBron James and some teammates practiced free throws at a nearby basket, coach Tyronn Lue addressed questions about the troubling state of the Cavaliers while sitting in a high-backed, cushioned chair.While he was cool, Lue’s seat has warmed up.ADVERTISEMENT “This is kind of just my experience with this team, to be honest,” said forward Kyle Korver, acquired last January in a trade. “The year that I’ve been here, we’ve been really good and we’ve been really bad. It seems to come in waves, so, hopefully there’s a good wave coming soon.”With all that’s wrong, changes would seem to be in order. Lue, though, believes the Cavs can solve their problems without any major alterations.“It’s the same group we won 18 out of 19 with also,” he said, referring to Cleveland’s stretch from Nov. 11 to Dec. 19. “We’ve just got to play better. We’ve got to play better, we’ve got to be sharper and that’s what we continue to keep working on. It’s the same team that won 18 out of 19 and 13 in a row.”Technically, Lue’s right. The Cavs’ roster hasn’t been touched — not yet.However, the club has been in almost continuous flux over the past month as key players Isaiah Thomas and Tristan Thompson returned from injuries. Also, reserves Jose Calderon, Channing Frye and Cedi Osman have seen their playing time diminish and Korver, the sharpshooter who had developed into the team’s best crunch-time player other than James, has had his role reduced.ADVERTISEMENT Steam emission over Taal’s main crater ‘steady’ for past 24 hours Lue has been searching for the right combinations, but the Cavs aren’t connecting.“We’re just figuring out our team,” Korver said. “Ty’s got a tough job. He’s trying to find lineups that are working and he’s trying to find minutes for everybody. I think he’s doing a great job in that regard, as far as getting everybody in the game. Maybe not Channing, we’d like to get Channing out there a little more but it’s a numbers thing right now.“It’s tough. There’s a numbers thing right now. Definitely I’ve been a part of that, too. It’s a long season. We’re riding a bad wave right now, but hopefully we’ll find some things that will start working again. Guys are getting healthier but we need to get back in sync. There’s no answers right now.”A demanding schedule and injuries have prevented the Cavs from practicing much, but they held their third workout this week. It was needed.Lue, though, decided not to show his players film of the debacle against Oklahoma City.“Just move on,” he said.Lue can’t be absolved from blame, but players aren’t faulting him for the team’s many issues, some of which could be addressed before the Feb. 8 trade deadline.Following Saturday’s head-scratching loss, James said he “would hope not” when asked if he thought Lue would be fired. Dwyane Wade dismissed any outside noise condemning the only Cleveland coach to win a championship since 1964.Those endorsements should help Lue, but he knows better than anyone how quickly change can come.Two years ago, Cavs owner Dan Gilbert fired David Blatt despite the team’s 30-11 record and replaced him with Lue, who at the time was the NBA’s highest-paid assistant. Cleveland doesn’t have a comparable situation now, and while there are no signs pointing to Lue being in imminent danger, anything is possible until the Cavs start stringing together some wins. Kerber pulls through a surprising challenge, faces Keys next Newsome sets focus on helping Bolts open new PBA season on right track Jiro Manio arrested for stabbing man in Marikina Carpio hits red carpet treatment for China Coast Guard PLAY LIST 02:14Carpio hits red carpet treatment for China Coast Guard02:56NCRPO pledges to donate P3.5 million to victims of Taal eruption00:56Heavy rain brings some relief in Australia02:37Calm moments allow Taal folks some respite03:23Negosyo sa Tagaytay City, bagsak sa pag-aalboroto ng Bulkang Taal01:13Christian Standhardinger wins PBA Best Player award With the Cavs mired in a bewildering midseason slump and less than 24 hours after a historically embarrassing loss to Oklahoma City, Lue said he has no immediate plans to change his starting lineup or rotations. Cleveland fans may be panicking, Lue’s not nervous.At least not publicly.FEATURED STORIESSPORTSTim Cone, Ginebra set their sights on elusive All-Filipino crownSPORTSGinebra beats Meralco again to capture PBA Governors’ Cup titleSPORTSAfter winning title, time for LA Tenorio to give back to Batangas folkThe Cavs are just 4-10 since Dec. 19, and in the past two weeks they’ve lost by 28 at Minnesota, 34 at Toronto and 24 to the Thunder, who scored 148 points and tied a record for the most points allowed by Cleveland in a regulation game — a mark that went unmatched since 1972.It’s a mess, and it’s a mystery the way James and the Cavs have collapsed. They’ve slipped in the past, but this slide feels much more ominous than in the previous three years when Cleveland stumbled but still reached the Finals. Almazan vows to comeback stronger after finals heartbreak Michael Porter Jr. stays patient as playing time increasescenter_img Lue can only do so much, and following similar comments by Thomas and Wade on Saturday, Korver said it’s imperative for Cleveland’s players to hold each other more accountable.“You’ve just got to look at yourself in the mirror and say ’What can I do better?’” Korver said. “You can’t point the finger. You can’t get mad at a guy for not doing what you thought he should’ve done. You just can’t point fingers. It’s really simple but it really is true. … We’re all grown-ups. When you’re a mature grown up you just look yourself in the mirror.”Sports Related Videospowered by AdSparcRead Next OSG plea to revoke ABS-CBN franchise ’a duplicitous move’ – Lacson MOST READ Don’t miss out on the latest news and information. Lights inside SMX hall flicker as Duterte rants vs Ayala, Pangilinan anew LATEST STORIES Nonito Donaire vs Naoya Inoue is BWAA 2019 Fight of the Year OSG plea to revoke ABS-CBN franchise ’a duplicitous move’ – Lacson View commentslast_img read more

TEMPE Ariz — Arizona Cardinals rookie safety Deo

first_imgTEMPE, Ariz. — Arizona Cardinals rookie safety Deone Bucannon has all of the physical tools necessary to be successful on the field in the NFL. The Cardinals’ first-round draft pick also knows that doesn’t mean anything when it comes to playing at football’s highest level. “Everyone out here has the physical tools to be a great player; it’s just a matter of who’s going to be smarter,” Bucannon said Tuesday after the team’s first minicamp practice. “That’s my goal, to be the smartest player out there. I want to learn the playbook the best I can.” The 5: Takeaways from the Coyotes’ introduction of Alex Meruelo Bucannon has plenty of experience with what it takes to be successful on the football field. He was named a first-team All-American and first-team All-Pac-12 in his final season at Washington State, and he led the conference in both interceptions and tackles. But the 6-foot-1, 208-pounder didn’t rack up those stats purely through physical ability — though he has plenty of that, too. Bucannon said he prides himself on being one of the smartest players on the field, and that’s something he expects to continue into his NFL career. “There’s always room for improvement,” he said. “I understand the defense, now I want to take it to the next level. I want to be a playmaker.”Cardinals coach Bruce Arians said Bucannon took an important step Tuesday after missing time with a foot injury during OTAs last week, adding that “he needs it, psychologically, just to get out there to play.”Bucannon’s knowledge of the game and ability to quickly understand schemes and concepts hasn’t gone unnoticed on teammates — particularly ones he’ll share a defensive backfield with. “He can do it all,” safety Rashad Johnson said. “He’s a very smart guy and I’m looking forward to what he’s going to do this year.” Top Stories Former Cardinals kicker Phil Dawson retires Derrick Hall satisfied with D-backs’ buying and selling Comments   Share   Grace expects Greinke trade to have emotional impact And if Bucannon has his way, Johnson will have a lot to enjoy watching in 2014. “I expect a lot out of myself,” Bucannon said, “and I’m going to get a lot out of myself.” – / 11last_img read more

Antibacterial substance found in toothpaste may fight against lifethreatening lung disease

first_imgMay 17 2018A common antibacterial substance found in toothpaste may combat life-threatening diseases such as cystic fibrosis, or CF, when combined with an already FDA-approved drug.Michigan State University researchers have found that when triclosan, a substance that reduces or prevents bacteria from growing, is combined with an antibiotic called tobramycin, it kills the cells that protect the CF bacteria, known as Pseudomonas aeruginosa, by up to 99.9 percent.CF is a common genetic disease with one in every 2,500 to 3,500 people diagnosed with it at an early age. It results in a thick mucus in the lungs, which becomes a magnet for bacteria.These bacteria are notoriously difficult to kill because they are protected by a slimy barrier known as a biofilm, which allows the disease to thrive even when treated with antibiotics.”The problem that we’re really tackling is finding ways to kill these biofilms,” said Chris Waters, lead author of the study and a microbiology professor.According to Waters, there are many common biofilm-related infections that people get such as ear infections and swollen, painful gums caused by gingivitis. But more serious, potentially fatal diseases join the ranks of CF including endocarditis, or inflammation of the heart, as well as infections from artificial hip and pacemaker implants.The research is published in the journal Antimicrobial Agents and Chemotherapy.Waters and his co-authors, Michael Maiden and Alessandra Hunt, grew 6,000 biofilms in petri dishes, added in tobramycin along with many different compounds, to see what worked better at killing the bacteria. Twenty-five potential compounds were effective, but one stood out.”It’s well known that triclosan, when used by itself, isn’t effective at killing Pseudomonas aeruginosa,” Hunt said, a post-doctoral associate of microbiology and molecular genetics. “But when I saw it listed as a possible compound to use with tobramycin, I was intrigued. We found triclosan was the one that worked every time.”Related StoriesNew methods to recognize antimicrobial resistant bacteria and how they workNew research links “broken heart syndrome” to cancerGene modulation goes wireless hacking the “boss gene”Triclosan has been used for more than 40 years in soaps, makeup and other commercial products because of its antibacterial properties. Recently, the FDA ruled to limit its use in soaps and hand sanitizers due to insufficient data on its increased effectiveness and concern that it was being overused. Clear evidence has shown, though, that its use in toothpaste is safe and highly effective in fighting gingivitis, and it is still approved for use.”Limiting its use is the right thing to do,” Maiden said, a graduate student in medicine. “The key is to avoid creating resistance to a substance so when it’s found in numerous products, the chances of that happening increase.”Tobramycin is currently the most widely used treatment for CF, but it typically doesn’t clear the lungs of infection, Waters said. Patients typically inhale the drug, yet find themselves chronically infected their whole lives, eventually needing a lung transplant.”Most transplants aren’t a viable option though for these patients and those who do have a transplant see a 50 percent failure rate within five years,” he said. “The other issue is that tobramycin can be toxic itself.”Known side effects from the drug include kidney toxicity and hearing loss.”Our triclosan finding gives doctors another potential option and allows them to use significantly less of the tobramycin in treatment, potentially reducing its use by 100 times,” Hunt said.Within the next year, Waters and his colleagues will begin testing the effectiveness of the combination therapy on mice with hopes of it heading to a human trial soon after since both drugs are already FDA approved.Just brushing your teeth with toothpaste that has triclosan won’t help to treat lung infections though, Maiden said.”We’re working to get this potential therapy approved so we can provide a new treatment option for CF patients, as well as treat other biofilm infections that are now untreatable. We think this can save lives.”Source: https://msutoday.msu.edu/news/2018/ingredient-in-your-toothpaste-may-combat-severe-lung-disease/last_img read more